Stephen M Strittmatter Selected Research

Focal Adhesion Kinase 1

12/2016	Oligomers of Amyloid β Prevent Physiological Activation of the Cellular Prion Protein-Metabotropic Glutamate Receptor 5 Complex by Glutamate in Alzheimer Disease.
2/2016	Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer's disease.

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Stephen M Strittmatter Research Topics

Disease

41	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 02/2006
19	Spinal Cord Injuries (Spinal Cord Injury) 01/2022 - 05/2003
11	Wounds and Injuries (Trauma) 01/2022 - 05/2003
5	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2021 - 11/2010
4	Stroke (Strokes) 11/2021 - 07/2004
3	Cognitive Dysfunction 10/2021 - 12/2019
3	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2021 - 06/2012
3	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2017 - 10/2010
3	Crush Injuries 11/2016 - 09/2012
3	Contusions 12/2014 - 01/2009
2	Neuroinflammatory Diseases 01/2021 - 11/2020
2	Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis) 01/2021 - 11/2014
2	Tauopathies 01/2020 - 10/2019
2	Frontotemporal Dementia (Semantic Dementia) 07/2017 - 11/2010
2	Retinal Degeneration 07/2017 - 11/2014
2	Memory Disorders (Memory Loss) 01/2017 - 01/2015
2	Infarction (Infarctions) 10/2016 - 03/2010
2	Ganglion Cysts (Ganglion) 02/2015 - 03/2012
2	Amyloid Plaque 10/2010 - 02/2006
2	Traumatic Brain Injuries (Traumatic Brain Injury) 07/2010 - 01/2006
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 11/2009 - 09/2009
2	Schizophrenia (Dementia Praecox) 03/2009 - 12/2008
2	Cicatrix (Scar) 02/2007 - 09/2006
2	Spinal Injuries (Spinal Injury) 05/2005 - 11/2004
1	Inflammation (Inflammations) 01/2022
1	Gaucher Disease (Gaucher's Disease) 01/2021
1	Dementia (Dementias) 01/2020
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 10/2019
1	Demyelinating Diseases (Demyelinating Disease) 10/2019
1	Diarrhea 10/2019
1	Scrapie 01/2019
1	Prion Diseases (Transmissible Spongiform Encephalopathies) 01/2019
1	Ischemic Stroke 10/2016
1	Neuralgia (Stump Neuralgia) 01/2016
1	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 01/2016
1	Glaucoma 02/2015
1	Pneumonia (Pneumonitis) 01/2015
1	Heart Failure 01/2015

Drug/Important Bio-Agent (IBA)

24	Proteins (Proteins, Gene)FDA Link 01/2022 - 12/2004
21	Amyloid (Amyloid Fibrils)IBA 01/2022 - 02/2006
15	Nogo Receptor 1IBA 01/2021 - 05/2003
13	Prion ProteinsIBA 10/2019 - 11/2009
10	Peptides (Polypeptides)IBA 01/2022 - 02/2006
9	Nogo ReceptorsIBA 01/2020 - 11/2003
9	Amyloid beta-PeptidesIBA 01/2019 - 12/2006
5	ProgranulinsIBA 01/2021 - 11/2010
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 09/2009
4	LigandsIBA 01/2021 - 10/2002
4	Phosphotransferases (Kinase)IBA 01/2020 - 01/2013
3	saracatinibIBA 12/2019 - 01/2015
3	Metabotropic Glutamate 5 ReceptorIBA 01/2017 - 02/2016
3	Pharmaceutical PreparationsIBA 10/2016 - 02/2009
2	Glutamic Acid (Glutamate)FDA Link 01/2020 - 12/2016
2	Focal Adhesion Kinase 1IBA 12/2016 - 02/2016
2	Calcium-Calmodulin-Dependent Protein KinasesIBA 12/2016 - 02/2016
2	Ibuprofen (Motrin)FDA LinkGeneric 01/2016 - 01/2009
2	Growth InhibitorsIBA 06/2012 - 05/2012
2	Myelin-Associated GlycoproteinIBA 07/2010 - 11/2004
2	Oligodendrocyte-Myelin GlycoproteinIBA 07/2010 - 11/2004
1	IntegrinsIBA 01/2022
1	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 01/2022
1	2- (2- (dimethylaminomethylphenylthio))- 5- fluoromethylphenylamineIBA 01/2022
1	Serotonin (5 Hydroxytryptamine)IBA 01/2022
1	Lipid Droplet Associated ProteinsIBA 01/2022
1	Vacuolar Proton-Translocating ATPases (V-Type ATPase)IBA 01/2021
1	LipidsIBA 01/2021
1	conduritol epoxideIBA 01/2021
1	B-Cell Activating FactorIBA 01/2021
1	Apolipoproteins E (ApoE)IBA 01/2021
1	Indicators and Reagents (Reagents)IBA 01/2020
1	1- ((3- (methylpyridin- 4- yl)methyl)- 4- (3,4,5- trifluorophenyl)pyrrolidin- 2- oneIBA 12/2019
1	Actins (F Actin)IBA 01/2019
1	Messenger RNA (mRNA)IBA 01/2018
1	Nociceptin ReceptorIBA 01/2018
1	NociceptinIBA 01/2018
1	Opioid Analgesics (Opioids)IBA 01/2018
1	LipofuscinIBA 07/2017
1	florbetapirIBA 01/2017
1	3,5-dihydroxyphenylglycineIBA 12/2016
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 11/2016
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 11/2016
1	veliparibIBA 11/2016
1	ChlorotoxinIBA 10/2016
1	regadenoson FDA Link 10/2016
1	Indomethacin (Indometacin)FDA LinkGeneric 01/2016
1	mu-CrystallinsIBA 11/2015
1	Neuroprotective AgentsIBA 02/2015
1	GoldIBA 02/2015
1	Ethosuximide (Zarontin)FDA LinkGeneric 01/2015
1	brivaracetamIBA 01/2015
1	Glucose (Dextrose)FDA LinkGeneric 01/2015
1	lipopigmentsIBA 11/2014
1	CeroidIBA 11/2014

Therapy/Procedure

13	Therapeutics 11/2020 - 05/2003
2	Activities of Daily Living (ADL) 10/2019 - 01/2015
2	Axotomy 06/2019 - 09/2012
1	Microspheres (Microsphere) 02/2015
1	Nerve Crush 02/2015
1	Intraventricular Infusions 12/2014
1	Laminectomy 08/2014